Like Fiscal Fizzle, I'm trying to consolidate as much as possible, reducing the number of accounts and institutions where I keep my money. I have an extra incentive to do so, because I'm a dual US-Canadian citizen living in Canada, and I have to fill out a form every year for the IRS listing every bank account and investment I own in Canada, its account number, and its maxiumum value during the previous year. The fewer accounts I have, the easier it is to fill out that form.
Like others, I automate as much as possible; another thing I do is to receive and pay most of my bills online. I never keep any paper copies of my bills; instead, I use the built-in free PDF creator in my Mac to save all bills and payment receipts electronically to my computer with one click. I save them to a folder that's backed up automatically to a secure offsite server, so if anything happens (someone steals my computer, the house burns down, etc.), I'll still have a record of all my bills, payments, receipts, etc.
I only receive one or two bills by mail now, all the rest are online. I don't worry about trying to organize my electronic receipts because they're all instantly searchable; if I need to find one, I just do a search for the name of the vendor and all bills from that vendor come up. I use Quicken to track all my income and expenses, so I have that as a record too. There's a way to attach receipts to your Quicken records, but my approach is easier and simpler.