First welcome to the forums!
Second you should approach this potential solution (small business) with eyes wide open. Owning and working your own small business is not as glamerous as it may sound. I have friends who are doing this and basically they live for their small business. Small business owners work really hard (and sometimes harder), in my opinion, than people who end up working for a company. Keep in mind that 50% of small business startups fail in the first four or five years. Also keep in mind that most small businesses do not see a profit for the first year or two. (My cousin owns his own small business as a web designer and graphics design consultant. It's tough work. When business is good things are great and he can pay his bills. When business is bad things are really horrible and they struggle.)
Third it takes a certain personality to own your business. Are you self-motivated? Are you self-disciplined? Can you endure under pressure? See this article
for Common Characteristics of Successful Entrepreneurs.
Fourth what kind of business capital (assets) do you have? How much $$ do you have? Who would be the investors (family? friends? a bank?) for the small business startup? Do you live with family or on your own?
Fifth you say that your particular degree is in Secondary Education in a state that is laying off teachers. Have you considered moving to another state? I realize this would mean re-certification but relocation could possibly be just the solution for you.
Sixth here are some other alternatives:
A) Have you considered writting a book? eBooks are rather easy to write and easy to self-publish.
B) Have you considered opening up your own bake shop?
C) Have you considered opening up your own cleaning business?
D) Have you considered opening up your own lawn car service? (This can be great part-time weekend work especially now in the summer while your looking for something else.)
F) Have you considered going back to school and pursing a masters in education to become more marketable?
Hope this get's you at least pointed in the right direction. Chin up everyone had to start somewhere!