I recently relocated from New York City to Madison, Wisconsin. I made the move in order to have a lower cost of living, and to give me more flexibility to focus on things that will really make me and my family happy.
Most people think this is an extreme move that they could not do. But maybe you can. I am married with two small children, and I am a person who has always lived in big, expensive cities: Boston, Los Angeles, Chicago and New York. But the move turned out well for me.